The meeting focused on uses of ontologies, with a special focus on spatial ontologies, in addressing the ever increasing needs faced by biology and medicine to cope with ever expanding quantities of data. To provide effective solutions computers need to integrate data deriving from myriad heterogeneous sources by bringing the data together within a single framework. The meeting brought together leaders in the field of what are called "top-level ontologies" to address this issue, and to establish strategies among leaders in (...) the field of biomedical ontology for the creation of interoperable biomedical ontologies which will serve the goal of useful data integration. (shrink)

This detailed and enlightening work synthesizes modern biology and traditional religious doctrines. The result of this synthesis is the creation of a cohesive worldview, and, from there, the emergence of a compelling morality. The author argues that as individuals and as groups, we have the opportunity to change old beliefs and to embrace more plausible ones that can help us to establish a secure existence.

Religious naturalism is an emerging construct that relies greatly on science and yet affirms attitudes and practices that are distinctly religious in nature. This article explores the meaning of the term as it is used by various proponents, contrasts it to some similar constructs , and examines some objections andoutstanding issues from within the science‐religion community: postmodernist objections; whether religious naturalism is sufficiently respectful of traditional religious expression; and whether religious naturalism seeks to be a descriptive or a prescriptive enterprise (...) or both. Overall, religious naturalism is affirmed as a potentially productive new variant of naturaltheology, one that can preserve religious sensibilities without relying on supernatural constructs while maintaining a basic affirmation of other religious traditions. (shrink)

In his prophetic book Amythia, Loyal Rue calls for the construction of bold new myths. Responding to his call in light of scientific arguments for global population equilibrium, this article proposes a model that may function as a surrogate form of myth, one that can motivate our age and future ages. Fortunately, the model is not only powerful but achievable, because policy makers have finally begun to realize how thoroughly the human population impacts on other world dynamics. The problem is (...) reviewed, the relevance of scientific and theological studies bearing on it is shown, and the new model is described. Above all, an effort is made to show how global equilibrium can support Rue's twin requirements for the myth he commissions: namely, a foundation in plausible descriptions of reality, and a compelling normative status. (shrink)

The forty‐ninth annual IRAS conference on Star Island pursued the science‐religion dialogue primarily in terms of two concepts: nature and transcendence. Robust Yes responses and likewise robust No responses were presented by both scientists and theologians to the theme question, “Is Nature Enough? The Thirst for Transcendence.” After this introductory survey of the definitional landscape, representative papers from the conference are presented.

Michael Ruse's forthcoming book gives an enjoyable history of teleology in biology, philosophy, and theology. It argues that concepts of cause, final cause, purpose, teleology, function, design, adaptation, contrivance, progress, ends, and value have all been telescoped by most writers in those three disciplines but that these concepts (and especially the concept of design) are nonetheless valid, provided only that we recognize their metaphorical nature. I agree with this basic argument, and Ruse's critiques and historical summaries of these concepts (...) are both useful and delightful. However, I also explore one major and three minor reservations. The minor reservations are that Ruse overdoes the allegation of telescoping, does not adequately explore ways to express teleology more accurately, and erroneously denies the existence of biology–based theologians who make the same point he is making. The major reservation is that, despite all the groundwork he lays, Ruse comes to a conclusion other than the one clearly suggested by his first fourteen chapters. If he followed the evolutionary story just a bit further, to include the evolution of the human brain, he would be in a position to articulate a theologically sophisticated understanding of teleology and avoid an ending that is uncharacteristically tame. (shrink)

Laudan's "progress and its problems" is of two, incompatible, minds. proto-laudan argues that science is indexed to historical contexts, such that scientific rationality depends on progress and not vice-versa. deutero-laudan claims that sociology assumes "a rationality" and so misunderstands science. the latter is confused and offers no argument against sociology which does not also apply against historical approaches to philosophy of science, proto-laudan included. such tribal warfare is unprogressive, and best abandoned.

Zygon has been discussing the implications of sociobiology for twenty‐five years, ever since E. O. Wilson's book by that name first burst upon the stage. In the course of that discussion there have been many heated exchanges, but in this journal, at least, the heat has also generated light. Thus it is now timely and useful to review and consolidate Zygon's approach to the sociobiology construct, not only as it was originally presented but as it has changed over time. The (...) goal of this article is to recapitulate and summarize the dialogue that has taken place here. But my aim is not merely to rehash the discussion; it is more precisely to extend and continue it. Specific proposals are offered that are designed to ground future conversations on the solid foundation that has been established over the last quarter century. (shrink)

Many of us not part of the “old Burhoe gang” are nonetheless deeply influenced by the ideas of Ralph Wendell Burhoe, albeit in indirect ways. This remembrance summarizes six such ways: Three are “procedural” influences, namely (1) that dialogue is most valuable, especially in the science/religion interface, when carried on among those who may not agree; (2) that scholarship is necessary to refine and improve preliminary opinions; and (3) that organizations are crucial to accomplishing the first two tasks. The three (...) “substantive” influences are (4) Burhoe's focus on human values; (5) his work in defining God; and (6) his contribution to defining what it means to be human. As is well known, his emphasis in all three substantive cases was on the power and nuances of biological and social evolution, especially on the dynamics of natural selection. (shrink)

The value of any kind of data is greatly enhanced when it exists in a form that allows it to be integrated with other data. One approach to integration is through the annotation of multiple bodies of data using common controlled vocabularies or ‘ontologies’. Unfortunately, the very success of this approach has led to a proliferation of ontologies which itself creates obstacles to integration. The Open Biomedical Ontologies (OBO) consortium has set in train a strategy to overcome this problem. Existing (...) OBO ontologies, including the Gene Ontology, are undergoing a process of coordinated reform and new ontologies being created on the basis of an evolving set of shared principles governing ontology development. The result is an expanding family of ontologies designed to be interoperable, logically well-formed, and to incorporate accurate representations of biological reality. We describe the OBO Foundry initiative, and provide guidelines for those who might wish to become involved. (shrink)

This collection of essays represents the work of fifteen scholars in four disciplines: philosophy, theology, sociology, and cultural studies. It offers an interdisciplinary reflection on the role and impact of technology in society, focusing on the i.

Gravitational interactions allowed astronomers to conclude that dark matter rings all luminous galaxies in gigantic halos, but this only accounts for a fraction of the total mass of dark matter believed to exist. Where is the rest? We hypothesize that some of it resides in dark galaxies, pure dark matter halos that either never possessed or have totally lost their baryonic matter. This article explores methodological challenges that arise because of the nature of observation in astrophysics and examines how the (...) blend of observation, simulation, and theory we call the Observing the Invisible approach might make detecting such dark objects possible. (shrink)

We conducted focus groups with 47 potential jurors who were presented with diferent scenarios in a hypothetical malpractice case involving failure to order a PSA test. Better documentation that a patient made an informed decision to decline a PSA test appeared to provide more medical-legal protection for physicians, especially with the use of a decision aid.

Screening for prostate cancer with the prostate-specific antigen blood test is controversial, as evidence to date has not demonstrated such screening does more good than harm. While the potential benefit of PSA screening on reducing prostate cancer mortality has not been documented in randomized trials, many risks of PSA screening have been well documented. These risks include a substantially higher risk of a prostate cancer diagnosis over a screenee’s lifetime, false-positive and false-negative test results, possible complications from biopsies done in (...) response to suspicious test results, and substantial risks of side effects from subsequent prostate cancer treatments. Nevertheless, PSA screening is widespread in the United States, and many physicians in a national survey reported supporting routine PSA screening as well as getting PSA tests themselves, despite the lack of evidence. (shrink)

Ontology is one strategy for promoting interoperability of heterogeneous data through consistent tagging. An ontology is a controlled structured vocabulary consisting of general terms (such as “cell” or “image” or “tissue” or “microscope”) that form the basis for such tagging. These terms are designed to represent the types of entities in the domain of reality that the ontology has been devised to capture; the terms are provided with logical defi nitions thereby also supporting reasoning over the tagged data. Aim: This (...) paper provides a survey of the biomedical imaging ontologies that have been developed thus far. It outlines the challenges, particularly faced by ontologies in the fields of histopathological imaging and image analysis, and suggests a strategy for addressing these challenges in the example domain of quantitative histopathology imaging. The ultimate goal is to support the multiscale understanding of disease that comes from using interoperable ontologies to integrate imaging data with clinical and genomics data. (shrink)

This article argues that correctional institutions violate the Eighth Amendment when they refuse to establish MAT programs and prevent doctors from exercising medical judgment to properly treat incarcerated people with OUD.

This comprehensive Handbook presents the major perspectives within philosophy and literary studies on the relations, overlaps and tensions between philosophy and literature. Drawing on recent work in philosophy and literature, literary theory, philosophical aesthetics, literature as philosophy and philosophy as literature, its twenty-nine chapters plus substantial Introduction and Afterword examine the ways in which philosophy and literature depend on each other and interact, while also contrasting with each other in that they necessarily exclude or incorporate each other. This book establishes (...) an enduring framework for structuring the broad themes defining the relations between philosophy and literature and organising the main topics in the field. Key Features • Structured in five parts addressing philosophy as literature, philosophy of literature, philosophical aesthetics, literary criticism and theory, and main areas of work within philosophy and literature • An Introduction setting out the main concerns of the field through discussion of the major themes along with the individual topics • An Afterword looking at the interactions between philosophy and literature through itself enacting philosophical and literary writing while examining the question of how they can be brought together The Palgrave Handbook of Philosophy and Literature is an essential resource for scholars, researchers and advanced students in philosophy of literature, philosophy as literature, literary theory, literature as philosophy, and the philosophical aesthetics of literature. It is an ideal volume for researchers, advanced students and scholars in philosophy, literary studies, philosophy and literature, cultural studies, classical studies and other related fields. (shrink)

Socrates is still an enigmatic figure of enormous importance in Western culture. This book introduces both some of Socrates' problems and some of the problems about him. It seeks at the same time to advance new views, arguments and information on Socrates' mission, techniques, ethics and later reception. Composed of new essays by different scholars, some of them primarily Hellenstics, some philosophers, it illustrates both the variety of Plato's literary portrayals of Socrates and the diversity of later and present-day approaches (...) to him. Socratic Questions thus confronts the difficulties, philosophical and biographical, presented by dialogues such as Protagoras and Crito and by the Apology of Socrates. From civil disobedience to ethics, this collection provides stimulating discussions of Socrates' life, thought and historical significance. It will be of great interest to all students of ancient Greek history literature and philosophy. (shrink)

How do we find what is clinically significant in the swarms of data being generated by today’s diagnostic technologies? As electronic records become ever more prevalent – and digital imaging and genomic, proteomic, salivaomics, metabalomics, pharmacogenomics, phenomics and transcriptomics techniques become commonplace – fdifferent clinical and biological disciplines are facing up to the need to put their data houses in order to avoid the consequences of an uncontrolled explosion of different ways of describing information. We describe a new strategy to (...) advance the consistency of data in the dental research community. The strategy is based on the idea that existing systems for data collection in dental research will continue to be used, but proposes a methodology in which past, present and future data will be described using a consensus-based controlled structured vocabulary called the Ontology for Dental Research (ODR). (shrink)

This academic text features articles regarding paranormal, extraordinary, or fringe-science claims. It logically examines the claims of astrology; psychic ability; alternative medicine and health claims; after-death communication; cryptozoology; and faith healing, all from a skeptical perspective. Paranormal Claims is a compilation of some of the most eye-opening articles about pseudoscience and extraordinary claims that often reveal logical, scientific explanations, or an outright scam. These articles, steeped in skepticism, teach critical thinking when approaching courses in psychology, sociology, philosophy, education, or science.

Letter commenting on the paper Barry Smith, Louis J. Goldberg, Alan Ruttenberg & Michael Glick, "Ontology and the Future of Dental Research Informatics", Journal of the American Dental Association 141 2010;(10):1173-75 with responses by the authors of the paper.

This multi-disciplinary collection interrogates the role of human rights in addressing past injustices. The volume draws on legal scholars, political scientists, anthropologists and political philosophers grappling with the weight of the memory of historical injustices arising from conflicts in Europe, the Middle East and Australasia. It examines the role of human rights as legal doctrine, rhetoric and policy as developed by states, international organizations, regional organizations, and non-governmental organizations. The authors question whether faith in human rights is justified as balm (...) to heal the past injustice or whether such faith nourishes both victimhood and self-justification. These issues are explored through three discrete sections: moments of memory and injustice, addressing injustice and questions of faith. In each of these sections authors address the manner in which memory of past conflicts and injustice haunt our contemporary understanding of human rights. The volume questions whether the expectations that human rights law can deal with the past injustice has undermined the development of an emancipatory politics of human rights for our current world. (shrink)